IndraLab

Statements

USP15 increases the amount of RAF1. 2 / 2
| 2
reach
"Furthermore we are able to demonstrate that USP15 also contributes to the regulation of sustained MAP kinase signaling after acute stimulation by modulating the expression level of the upstream kinase CRAF."
23105109
reach
"Rather we found a specific and significant impact of USP15 depletion on a luciferase reporter cloned upstream of the CRAF 3 '-UTR, suggesting that USP15 may modulate CRAF protein levels via an as yet identified mechanism involving its 3 '-UTR."
23105109