IndraLab

Statements

EGFR phosphorylates itself on Y1110. 6 / 6
| 6
sparser
"Serum dependent cyclin D1 expression in MCA is associated with Y1086 EGFR autophosphorylation."
19935697
sparser
"These combined data indicate that in lung epithelial cells, PTPµ selectively restrains EGFR autophosphorylation of Y845, Y992, Y1068, and Y1086."
18952113
sparser
"ZD1839 also suppressed EGF-induced stimulation of EGFR autophosphorylation on Y1086 and Y1068, MAPK phosphorylation on T402 and Y404, and Pak1 activity in a dose-dependent manner."
12700278
sparser
"This arrest was linked to epidermal growth factor receptor (EGFR)-Y1086 autophosphorylation, which inhibited AKT activation and cyclin D1 induction xref ."
25118602
sparser
"In addition, ZD1839 suppressed EGF-induced stimulation of EGFR autophosphorylation on Y1086 and Grb2-binding Y1068 sites, c-Src phosphorylation on Y215, and Pak1 activity."
14760089
sparser
"EGFR autophosphorylation of Y1086 provides the dominant but not exclusive docking site for the adaptor molecule Shc, which can, through its interaction with Grb2, elicit ERK1/2 activation [ xref ]."
21649524