IndraLab

Statements

CDK6 leads to the phosphorylation of USP17L2. 7 / 7
| 1 6
rlimsp
"(h) The working model to illustrate that CDK4/6 phosphorylation-dependent activation of DUB3 regulates epithelial–mesenchymal transition and metastasis through SNAIL1."
28067227
rlimsp
"As shown in Fig. 5d, mutation at S41 abolished CDK4/6-mediated phosphorylation of DUB3 in vitro."
28067227
rlimsp
"We hypothesized that CDK4/6 could phosphorylate DUB3."
28067227
rlimsp
"We next tested CDK4/6-mediated phosphorylation of DUB3 in cells."
28067227
reach
"Furthermore, depletion of CDK4 or CDK6 in cells only partially decreased the phosphorylation of DUB3, while double knockdown of CDK4 and CDK6 almost completely abrogated DUB3 phosphorylation (XREF_FIG)."
28067227
rlimsp
"(d) CDK4/6 phosphorylates DUB3 in vitro."
28067227
rlimsp
"CDK4/6 phosphorylates and activates DUB3."
28067227