IndraLab

Statements

AKT phosphorylates RAC1 at position 71. 3 / 3
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"Fourth, Akt phosphorylates serine 71 of Rac1 thereby modulating the Rac1 signal transduction pathway in SK-MEL-28 melanoma cells."
19493313
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"Thus, the results suggest that Akt kinase of the phosphoinositide 3-kinase signal transduction pathway phosphorylates serine 71 of Rac1 as one of its authentic substrates and modulates the Rac1 signal transduction pathway through phosphorylation."
10617634
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"On the other hand, phosphorylation of serine 71 on Rac1 by serine/threonine kinase Akt seems to have different effects - inhibiting the GTP binding activity of Rac1 with no significant change in GTPase activity [XREF_BIBR]."
22572609