IndraLab

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UCHL5 leads to the ubiquitination of SMAD3. 1 / 5
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"Consistent with the finding from using b-AP15, UCHL5 overexpression decreased poly-ubiquitination of Smad2 and Smad3 (XREF_FIG), while down-regulation of UCHL5 (~ 73%) by UCHL5 shRNA increased poly-ubiquitination of Smad2 and Smad3 (XREF_FIG)."