IndraLab

Statements

USP10 inhibits reactive oxygen species. 5 / 5
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"However, our results using USP10 functional mutants indicated that ROS inhibition by USP10 is dispensable for USP10 to inhibit apoptosis of HSCs."
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"On exposure to arsenic, an oxidative stress inducer, USP10 is recruited into stress granules (SGs), and USP10 containing SGs reduce reactive oxygen species (ROS) production and inhibit ROS dependent apoptosis."
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"However, our results using USP10 functional mutants indicated that ROS inhibition by USP10 is dispensable for USP10 to inhibit apoptosis of HSCs."
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"Upon exposure to an oxidant, USP10 inhibits ROS dependent apoptosis by reducing ROS production."
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"Similarly, USP10 and USP13 silencing could induce ROS generation and cause DNA damage."
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