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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

ZUP1 inhibits efficacy proIL-1b cleavage. 1 / 1

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eidos

"In line with this work , Zhang et al. [ 81 ] have shown that POH1 , a DUB that forms part of the 19S subunit of the proteasome , interacts with and deubiquitinates proIL-1b by decreasing the K63-linked polyubiquitin chains , as well as decreasing the efficacy of proIL-1b cleavage ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...