IndraLab

Statements


3 | 2 1

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"Importantly, the recruitment of CYLD to the TNFR1 complex depended on SPATA2 (XREF_FIG D)."

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"The fact that KO of SPATA2 already prevents association of CYLD with the TNFR1 ( xref D) indicates that SPATA2L cannot simply substitute for SPATA2, at least in the cellular systems tested."

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"As shown in Fig. 3B, the recruitment and ubiquitylation of RIPK1, and the subsequent, time dependent recruitment of TRADD, SHARPIN, and CYLD to the TNFR1 complex upon the addition of TNFalpha was unchanged in the presence of primidone."