IndraLab

Statements

IGF1R binds IRS1 and SMO. 2 / 2
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sparser
"The results suggest that the molecular mechanism by which Shh and IGF-I integrate their effect on myoblast proliferation and differentiation can already be found at the receptor level via an interaction of Smo with IGF-IR and IRS-1."
21618536
sparser
"Furthermore, we show that Smo activity is required for both Shh and IGF-I action and that the IGF-IR and its effector IRS-1 associate with Smo in response to these factors, suggesting that cross talk is already occurring at the receptor level."
21618536