IndraLab

Statements


CYLD activates miR-362-5p. 4 / 4
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"Mechanistic investigations confirmed that the tumor suppressor gene CYLD is a direct target of miR-362-5p."

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"CYLD, a negative regulator of NF-kappaB signaling, is a target of miR-362-5p in NK cells."

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"We also demonstrated that CYLD, a negative regulator of NF-kappaB signaling, was a target of miR-362-5p in NK cells."

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"Because NF-kappaB signaling is important in NK cell function XREF_BIBR XREF_BIBR XREF_BIBR and because CYLD is a direct target of miR-362-5p, we hypothesized that miR-362-5p likely regulates human NK cell function through the CYLD-NF-kappaB pathway."