IndraLab

Statements

CYLD inhibits ubiquitination. 5 / 6
| 5
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"In hepatic listeriosis, Cyld-deficiency increased K63-ubiquitination of STAT3, and further in vitro experiments demonstrated that CYLD inhibited K63-ubiquitination of STAT3 in the cytoplasm of IL-6-stimulated hepatocytes, which is in agreement with the exclusive cytoplasmic localisation of CYLD."
23825949
sparser
"CYLD can inhibit ubiquitination of the RIG1 cytoplasmic viral RNA sensor and also downregulate antiviral Interferon production by controlling IKK activation [ xref ]."
25342597
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"CYLD inhibits Tax ubiquitination."
21824392
sparser
"Deubiquitinating enzyme CYLD inhibits NEMO linear ubiquitination, possibly by disassembling both K63-linked and linear polyubiquitin."
21811235
sparser
"In addition, CYLD also inhibits the ubiquitination of TBK1 and IKKε, which also contributes to the negative regulation of IFN responses by CYLD xref ."
27012466