IndraLab

Statements

ATM phosphorylates USP10 on T42. 9 / 10
1 | 4 4
sparser
"The translocation and stabilization of USP10 is regulated by ATM -mediated phosphorylation of USP10 at Thr42 and Ser337."
20096447
reach
"Yuan et al. demonstrated that ATM could phosphorylate USP10 at Thr42 and Ser337 upon the DNA-damage response and USP10 was translocated into the nucleus, where the N-terminus of USP10 (amino acids 1–100) binds to p53 and inhibits its ubiquitination [27]."
35627217
sparser
"ATM phosphorylates USP10 on Thr 42 and Ser 337 , and this event is required for the stabilization of USP10 and its translocation into nucleus after DNA damage."
21480003
sparser
"Mechanistically, the phosphorylation of Thr42 and Ser337 of USP10 by ATM is required for USP10 translocation and stabilization."
20096447
reach
"In the case of DNA damage, the phosphorylation of USP10 at Thr42 and Ser337 mediated by ATM is essential for its translocation to the nucleus, where USP10 induces the deubiquitination of p53 and makes p53 work as a tumor suppressor."
32140262
reach
"ATM phosphorylates USP10 on Thr 42 and Ser 337, and this event is required for the stabilization of USP10 and its translocation into nucleus after DNA damage."
21480003
biopax:phosphositeplus
No evidence text available
sparser
"Yuan et al. demonstrated that ATM could phosphorylate USP10 at Thr42 and Ser337 upon the DNA-damage response and USP10 was translocated into the nucleus, where the N-terminus of USP10 (amino acids 1-100) binds to p53 and inhibits its ubiquitination [27] ."
35627217
reach
"Mechanistically, the phosphorylation of Thr42 and Ser337 of USP10 by ATM is required for USP10 translocation and stabilization."
20096447