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BAP1 deubiquitinates BRCA1. 3 / 4
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"Therefore, we opine that the BAP1/BRCA1 interaction inactivates the NF-κB signaling to protect septic AKI.In conclusion, this study demonstrates that BAP1 protects mice from sepsis-induced AKI by deub[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
37414201
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"We hypothesized that BAP1 might deubiquitinate BRCA1 and protect it from proteasome mediated degradation; this might explain the BRCA1 stabilization by the mutant BAP1 forms that retained the DUB activity."
26011428
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"As a possible mechanism of BRCA1 stabilization by BAP1 transduction in this study, we speculated that the ubiquitination of BRCA1 protein might be directly deubiquitinated by BAP1."
26011428