IndraLab

Statements

KCNMA1 activates Cell Survival. 5 / 5
| 5
reach
"Such beneficial effects of BK channel facilitation are consistent with the general recognition that BK channel activity supports cell survival and proliferation of various neural and non-neural cells [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
26051398
reach
"Thus, hslO-expressing plasmids support ΔrecA polA cell viability while inducting hslO expression."
36564489
reach
"The hslo dependent increase of the cell viability may have a role in the hypertrophic phenotype observed in disease conditions associated with hyperkalemia or abnormal K + ion homeostasis."
23874973
reach
"Finally, we tested the hypothesis that the downstream signaling pathway activated by the BK channel targeting compounds under study and resulting in the observed modulation of SH-SY5Y cell viability, may involve the serine threonine kinase AKT-1."
30126198
reach
"The BK channel openers restored the cell viability to control values under normokalemia conditions in the presence of IbTX and under hyperkalemia conditions in hslo-HEK293 cells and their effects were correlated with their efficacy in activating the BK channel currents."
23874973