IndraLab

Statements

KCNMA1 activates Cell Survival. 3 / 3
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reach
"Finally, we tested the hypothesis that the downstream signaling pathway activated by the BK channel targeting compounds under study and resulting in the observed modulation of SH-SY5Y cell viability, may involve the serine threonine kinase AKT-1."
30126198
reach
"The BK channel openers restored the cell viability to control values under normokalemia conditions in the presence of IbTX and under hyperkalemia conditions in hslo-HEK293 cells and their effects were correlated with their efficacy in activating the BK channel currents."
23874973
reach
"The hslo dependent increase of the cell viability may have a role in the hypertrophic phenotype observed in disease conditions associated with hyperkalemia or abnormal K + ion homeostasis."
23874973