IndraLab

Statements


ATXN3 activates Caspase. 3 / 3
| 2 1

reach
"The data with zVAD-fmk indicated that Ataxin-3 is a target of caspases also in Drosophila cells."

reach
"While it is reasonable to hypothesize that expanded Ataxin-3 protein may activate caspases that proteolyze Ataxin-3, the observation that normal Ataxin-3, which does not cause neurodegeneration, is also cleaved, suggests that cleavage is not necessarily a consequence of apoptosis."

sparser
"While it is reasonable to hypothesize that expanded Ataxin-3 protein may activate caspases that proteolyze Ataxin-3, the observation that normal Ataxin-3, which does not cause neurodegeneration, is also cleaved, suggests that cleavage is not necessarily a consequence of apoptosis."