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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

HACE1-S385A leads to the ubiquitination of RAC1-Q61L. 1 / 1

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"In accordance with our hypothesis, we found that the phospho mimetic mutant HACE1 (S385E) displays a reduced capacity to ubiquitinate Rac1 (Q61L) while the phospho resistant mutant HACE1 (S385A) induces Rac1 (Q61L) ubiquitination as efficiently as HACE1 (WT)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...