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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Mutations catalytic residues PLP-TM Cys1274Ser His1437Lys inhibits ZUP1. 1 / 1

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eidos

"In addition , mutations of the catalytic residues of PLP-TM , Cys1274Ser and His1437Lys , reduced DUB activity against Ub - , K48-and K63-conjugated proteins , indicating that the DUB activity of the PLP-TM wild-type protein is not completely dependent on its catalytic activity ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...