Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

PRMT6 methylates CDKN2A on R138. 2 / 2

| 1 1

➶

sparser

"PRMT6 methylates p16 at Arg22, Arg131 and Arg138 residues and promotes the cell cycle by inhibiting the interaction of p16 with CDK4 [ xref , xref ]."

| PMC

➶

reach

"Recently, we have demonstrated that p16 are methylated at Arg 22, Arg 131 and Arg 138 by PRMT6 and these modifications alleviated the cell cycle arrest at G1 via reducing p16-CDK4 interaction XREF_BIBR."

28120917

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...