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PSMD14 activates Hippo-YAP1. 2 / 2
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"GSEA revealed that the Hippo pathway and the YAP-UP pathway were highly enriched in PSMD14-high groups (Fig. 6A), suggesting that PSMD14 may activate the Hippo-YAP1 pathway to exert its oncogenic effects."

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"Furthermore, bioinformatics analysis identified NCL as a downstream target of PSMD14, leading to the hypothesis that PSMD14, through regulating NCL, activates the Hippo-YAP1 pathway to drive bladder cancer malignancy."