IndraLab

Statements

USP19 deubiquitinates LRP6. 2 / 2

1 | 1

"We show that folding of the Wnt signaling coreceptor LRP6 is promoted by ubiquitination of a specific lysine, retaining it in the ER while avoiding degradation. Subsequent ER exit requires removal of ubiquitin from this lysine by the deubiquitinating enzyme USP19."

27751231

➶

reach

"Upon release from this putative ubiquitin binding chaperone, LRP6 is deubiquitinated by USP19."

27751231

INDRA sources:

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IndraLab

Statements

USP19 deubiquitinates LRP6. 2 / 2

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