Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TGFBR1 phosphorylates phosphorylated SMAD3. 1 / 1

| 1

➶

reach

"In canonical TGF-β signaling, the C-terminal regions of the SMAD2 and SMAD3 proteins [23,24] are phosphorylated by the activated TBRI [25], allowing association with the co-mediator SMAD4 and nuclear accumulation of the SMAD2/3 complex where it can then regulate transcription of downstream genes [26]."

29718973

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...