IndraLab

Statements

BRAF binds HRAS and RAF1. 3 / 3
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"We observed that complexes of full-length BRAF and CRAF dimers are formed primarily in the presence of coexpressed HRAS and HRAS G12V . Complexes containing truncated BRAF hybrid proteins were slightly affected by RAS coexpression ( xref )."
31453322
sparser
"Following uptake of HFE-145-derived exosomes in recipient cells, GKN1 protein bound to HRas and inhibited the binding of HRas to b-Raf and c-Raf which subsequently downregulated HRas/Raf/MEK/ERK signaling pathways in AGS, MKN1 cells, and MKN1-derived xenograft tumor tissues."
32291710
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"B-Raf was shown to share almost the same H-Ras binding-specificity with Raf-1 by examining binding of the H-Ras mutants to Raf-1 and B-Raf in the yeast two-hybrid and in vitro binding assays."
8687465