Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CTNNB1 is transcriptionally active. 2 / 2

2 |

➶

bel

"IGF1R has been found in a complex with E-cadherin and ?-catenin and, following IGF2 stimulation, E-cadherin is internalized and degraded by an unknown mechanism. Subsequently, ?-catenin translocates from the plasma membrane to the nucleus, resulting in the modulation of ?-catenin-TCF target-gene expression"

14964308

➶

bel

"n the absence of Wnt stimulation, the level of beta-catenin is reduced via glycogen synthase kinase (GSK)-3beta-mediated phosphorylation and subsequent proteasome-dependent degradation."

17621269

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...