IndraLab

Statements

COPS5 decreases the amount of COPS5. 6 / 6
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"Since JAB1 knockdown significantly decreased nuclear JAB1 expression, but not clearly decrease cytoplasmic JAB1 expression, the decrease in nuclear JAB1 expression may cause the decrease in nuclear β-[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
32977947
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"Immunoblot analysis revealed that both CSN5 siRNA-1 and siRNA-2 efficiently repressed expression of CSN5 without affecting that of CSN1 and CSN8, suggesting that knockdown of CSN5 does not cause disru[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
12732143
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"Here, we report that transcription coactivator CSN5 interacts with the intracellular II-III linker of the alpha 1C subunit of cardiac L-type Ca 2+ channel in vivo and inhibits channel activity.Overexp[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
16483597
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"The loss of csn-5 does not decrease the levels of a related PUF protein PUF-3 and csn-5(lf) phenotype is not enhanced by fbf-1/2 knockdown, suggesting that the effect is specific to FBFs."
38427913
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"Firstly, we co-transfected cells with sh-COPS5 (COPS5 knockdown) and METTL3 OE (METTL3 overexpression), and determined METTL3 and COPS5 expression first; Fig. 6 A–B shows that COPS5 knockdown caused n[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36100071
reach
"As indicated in Fig. 7 A-B, COPS5 overexpression caused no changes in METTL3 expression but notably promoted COPS5 expression, whereas METTL3 knockdown observably inhibited METTL3 and facilitated COPS[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36100071