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COPS5 decreases the amount of COPS5. 2 / 2
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"Here, we report that transcription coactivator CSN5 interacts with the intracellular II-III linker of the alpha 1C subunit of cardiac L-type Ca 2+ channel in vivo and inhibits channel activity.Overexp[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Immunoblot analysis revealed that both CSN5 siRNA-1 and siRNA-2 efficiently repressed expression of CSN5 without affecting that of CSN1 and CSN8, suggesting that knockdown of CSN5 does not cause disru[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"