IndraLab

Statements

USP1 leads to the dephosphorylation of CHEK1. 2 / 2
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"In a prior study (Guervilly et al., 2011), USP1 depletion suppressed both Chk1 phosphorylation and steady-state levels in an FA-pathway-dependent manner, suggesting that FANCD2 monoubiquitination acts[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
28636932
reach
"In a prior study, USP1 depletion suppressed both Chk1 phosphorylation and steady state levels in an FA pathway dependent manner, suggesting that FANCD2 monoubiquitination acts to switch off Chk1 through a negative feedback mechanism."
28636932