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USP11 inhibits G1 S transition cells. 1 / 1
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eidos
"A 2018 study demonstrated that the loss of USP11 may cause p21 instability and induce G1 / S transition in cells ; in addition , the accumulation of p21 due to DNA damage was completely eliminated in cells lacking USP11 , which led to the abolition of the G2 checkpoint and the induction of apoptosis ( 41 ) ."