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USP14 activates pyroptosis. 2 / 2

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"USP14 promotes pyroptosis of human annulus fibrosus cells derived from patients with intervertebral disc degeneration through deubiquitination of NLRP3."

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"In this study, the role of USP14 in mediating the activation of the NLRP3 inflammasome and the pyroptosis of AF cells from IVDD patients is determined in vitro , and gain- and loss-of-function assays of USP14 and the NLRP3 inflammasome are conducted."

36514221

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USP14 activates pyroptosis. 2 / 2

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