IndraLab

Statements


| 7

sparser
"In addition, treatment of keratinocytes with TSA caused an increase in the interaction of CYLD with tubulin as compared with that in untreated cells ( xref )."

sparser
"For instance, Gao et al. identified that, Cyld interacts with tubulins, and the activity of this DUB is required for microtubule assembly and maintaining its stability."

sparser
"CYLD binds directly and indirectly to tubulin and microtubules via CG domains to regulate microtubule dynamics, with certain differences in tubulin-binding affinity and interacting partners among these CG domains [ xref ]."

sparser
"Interaction of CYLD with tubulin and MT."

sparser
"The alteration of MT dynamics and CYLDtubulin association is functionally linked to CYLD deubiquitylating activity and signaling ."

sparser
"Furthermore, exposure of keratinocytes ( xref ) or melanocytes ( xref ) to nocodazole, which depolymerises MTs, induced rapid dissociation of CYLD from MTs, suggesting that CYLD associates with polymerised tubulin."

sparser
"The interaction of CYLD with tubulin was confirmed by reverse immunoprecipitation of α-tubulin and subsequent immunoblotting against CYLD in melanocytes ( xref ) and in primary mouse keratinocytes ( xref )."