IndraLab
Statements
reach
"IL-6 increased phosphorylation of STAT3 (at Tyr (705)) and ERK1/2 (at Tyr (204)) within 5 min that peaked at 15-30 min and returned to basal levels at 2 h. Phosphorylation of STAT3 was blocked by genistein, a protein tyrosine kinase inhibitor, and AG490, a JAK2 inhibitor, but not PD98059, an ERK1/2 kinase inhibitor."