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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP7 binds MDM2 and ATM. 1 / 1

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"Mdm2 seems to be the preferred substrate for USP7 in unstressed cells, and genotoxic stress decreases USP7 binding to Mdm2 through ATM-dependent phosphorylation, shifting the balance toward p53 stabilization xref xref ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...