IndraLab

Statements



reach
"Furthermore, knockdown of UCHL5 by RNAi recapitulated the DUB-inhibited phenotype, indicating UCHL5 is likely the DUB responsible for MGRN1 deubiquitination."

reach
"Dual inhibition of USP14 and UCHL5, another DUB, was proven efficient in inhibiting the growth of patient-derived Bortezomib-resistant MM cells in both in vitro and in vivo conditions."

reach
"Assessment of DUB activity using recombinant proteins and in cell-based assays revealed that WP1130 inhibits USP5, USP9X, USP14, and UCH37, but not UCHL3."