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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP9X inhibits mitosis. 2 / 2

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"Control or USP9X depleted human osteosarcoma U2OS cells were arrested in mitosis with the microtubule destabilizing drug nocodazole for 2, 4, or 6hr to examine the rate of degradation of Mcl-1 and key mitotic regulators."

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"We found that USP9X depletion reduced the duration of the arrest and cells exited mitosis despite the presence of the drug (XREF_FIG B)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...