IndraLab

Statements


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sparser
"The result showed that Flag-GD-NT interacted with both OTUB1 and OTUB2 (Fig. xref )."

sparser
"On the other hand, OTU1-OTU3 comparisons showed four total upregulated and 88 downregulated genes in OTU1-dominated communities, whereas OTU1-OTU2 comparisons showed 751 total upregulated and 403 downregulated genes in OTU1-dominated communities ( xref )."

sparser
"Binding of Known Covalent SARS-CoV PLpro Inhibitors to OTUB2/OTUB1/SARS-CoV-2 PLpro."

sparser
"A coimmunoprecipitation (co-IP) assay using mutant PD-L1 or OTUB2 proteins with different structural domains deleted revealed the involvement of the ICD (261–290) of PD-L1 in the interaction with OTUB2 and the OTU domain (44–234) of OTUB2 in the interaction with PD-L1 (Fig.  xref )."

sparser
"Next, Kaplan-Meier's survival analysis was performed to examine the expression of five deubiquitinating enzymes in 117 NSCLC patients (GEO Submission: GSE13213) and revealed that the higher expression of OTUB1 and OTUB2 was significantly associated with poor patient prognosis (Figure xref B-EandFigure xref E)."

sparser
"OTUB1 and OTUB2 interact with and deubiquitinate TRAF3 and TRAF6, which are required for virus-triggered IRF3 and NF-κB activation [ xref ]."

sparser
"Since local resolution of the OTU domain was not sufficient to build a de novo molecular model, we determined the structure of the N-terminally extended Otu2-OTU domain comprising residues 150–307 by X-ray crystallography (Supplementary Table  xref and Supplementary Fig.  xref )."

sparser
"OTU1 and OTU2 ( R. radiotolerans ) associated to the meteorites ( p = 0.034), as did OTU5 ( Blastococcus sp.) p = 0.034, OTU6 ( G. pulveris ) p = 0.034, OTU12 (Chloroflexi) p = 0.028, OTU15 ( B. jejuensis ) p = 0.034, OTU19 (Frankiales) p = 0.034, OTU21 ( D. navajonensis ) p = 0.034, and OTU23 ( Rubrobacter sp.) p = 0.032."

sparser
"Therefore, we hypothesized that the cryo-EM electron density map presented the different orientation of OTU1-OTU2 domains with respect to each other and perhaps the domain orientation is variable in solution."