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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

SDC4 binds THY1 and ADAM15. 1 / 1

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sparser

"Considering that Thy-1 interacts with syndecan-4 and αvβ3, both astrocytic molecules, and that syndecan-4 levels are up-regulated in astrocytes following CNS injury ( xref ), as is also the case for the αvβ3 integrin ( xref ; xref ), the results reported by Fiore and colleagues ( xref ) suggest that the Thy-1/αvβ3 integrin/syndecan-4 complex may also exhibit dynamic catch bond behavior in our model system; however, whether this is indeed the case remains to be determined."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...