IndraLab

Statements

Cyclic AMP increases the amount of KCNA5. 2 / 2
2 |
bel
"# Ariadne: The transcription of a potassium channel gene, Kv1.5 , is regulated by glucocorticoids and cAMP in both GH3 cells and cardiac myocytes ( 16-18 ). [Expression]"
9030575
bel
"A cAMP response element (CRE) consensus signal was identified in the 5'-noncoding region. cAMP regulates the expression of Kv1.5 gene in a cell-specific manner. In primary cardiac cells, cAMP induces a 6-fold increase in the steady state levels of Kv1.5 transcript. However, in GH3 cells cAMP induces a 5-6-fold decrease in steady state levels of Kv1.5 transcript."
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