IndraLab

Statements


EGFR leads to the phosphorylation of MET on tyrosine. 3 / 3
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"It has been demonstrated that EGFR activation contributes to c-Met tyrosine phosphorylation in a variety of cell models, with varying kinetic parameters Since NSCLC commonly express both receptors, we examined whether EGFR ligands induce c-Met phosphorylation in human NSCLC cell lines."

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"It demonstrated that EGFR activation contributes to c-Met tyrosine phosphorylation [XREF_BIBR]."

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"Here, EGFR ligands induce prolonged c-Met tyrosine phosphorylation after a pronounced delay that is not attributable to an HGF-ligand autocrine production."