IndraLab

Statements

USP1 binds RAD51AP1 and FANCI. 2 / 2
| 2
sparser
"Importantly, the results revealed that neither mutant complex is able to catalyze FANCD2 deubiquitination (Fig.  xref , lanes 5 and 7) even though, as documented above and in Supplementary Fig.  xref , both UAF1 mutants retain all other known biochemical attributes, namely, interactions with RAD51AP1, USP1, and FANCI, and also the ability to enhance the DUB activity of USP1."
31253762
sparser
"Importantly, we have verified that UAF1 3A and UAF1 11A retain the ability to interact with USP1, RAD51AP1, and FANCI (Supplementary Fig.  xref ) and, with the Ub-VS DUB assay, to stimulate the DUB activity of USP1 (Supplementary Fig.  xref )."
31253762