
IndraLab
Statements
Thymine glycol inhibits IFIH1. 1 / 1
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"For example, both RECQL1 and FANCJ helicases are inhibited by thymine glycol residing within the duplex region in either the translocating or non-translocating strand [ xref ], suggesting that these helicases operate by an active mechanism in which they interact with both DNA strands during duplex DNA unwinding."