IndraLab

Statements


| 6

sparser
"This presumably reflects weaker and more gradual voltage-dependent Na + (and Ca 2+ ) channel activation in the spontaneously firing cells given their somewhat more positive resting potentials."

sparser
"This conditioning step would elicit a voltage-dependent Na + current activation as similarly achieved in the previous protocols that had been used to study Na + channel activation properties."

sparser
"To explore the effects of IL-6 on other aspects of voltage-gated Na + channels, we analyzed and compared voltage-dependent Na + channel activation and inactivation at different doses and various time points."

sparser
"This is not always the case, however, as 1,8-cineole, a terpenoid, was demonstrated to cause depolarization of the resting membrane and to block excitability, mainly indirectly, via the effect of depolarization voltage-dependent Na + current activation ( xref )."

sparser
"Hypocalcemia increases neuronal membrane excitability by reducing the threshold of voltage-dependent Na + channel activation [ xref ] and by directly interacting with channel gating machinery [ xref ]."

sparser
"A perturbative expansion of the non-dimensional membrane potential (Phi) is used to obtain time-dependent analytical solutions, involving a voltage-dependent Na(+) activation (micro) and a state-dependent inactivation (eta) gating variables."