IndraLab

Statements

TGFB1 phosphorylates SRC. 15 / 16
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"The present study demonstrates for the first time that activation of Smad signaling is partly dependent on non-ligand–mediated EGFR transactivation induced by TGF-β1–induced Src phosphorylation."
28943431
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"Here, we showed that TGF-beta1 strongly induced the phosphorylation of FAK, Src, and paxillin, while KY-05009 inhibited these inductions."
25337707
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"We show that TGF-beta1 activates the epidermal growth factor receptor (EGFR) and phosphorylates c-Src."
15856020
bel
"We show that TGF-beta1 activates the epidermal growth factor receptor (EGFR) and phosphorylates c-Src."
15856020
sparser
"CSE-mediated TGF-β1 activates the phosphorylation of FAK, Syk and Src to induce EMT processes in RPE cells."
29286114
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"TGF-beta1 has been reported to activate EGF signaling in hepatocytes by promoting the shedding of EGF like ligands and phosphorylation of Src."
23334091
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"CSE mediated TGF-beta1 activates the phosphorylation of FAK, Syk and Src to induce EMT processes in RPE cells."
29286114
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"Furthermore, TGF-β1-initiated Src phosphorylation of caveolin-1 Y14 is critical in Rho-ROCK-mediated suppression of the SMAD phosphatase PPM1A maintaining and, accordingly, SMAD2/3-dependent transcription of the PAI-1 gene."
31382626
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"Similarly, PP1 dose-dependently inhibited TGF-β1–induced Src phosphorylation (Tyr416), whereas total Src expression was not affected by this agent ( xref )."
26444028
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"Similarly with these results, the TGF-β1-induced phosphorylation of FAK and Src, and expression of α-smooth muscle action (SMA) were strongly inhibited in human normal lung fibroblast CCD-18Lu by CX-4945 ( xref )."
24023938
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"TGF-beta1 promoted epithelial-to-mesenchymal transition (EMT), invasion, Smad2/3 phosphorylation, Src activation, Wnt reporter activity, and Smad dependent upregulation of Wnt7b in KRC cells."
24334458
sparser
"Here, we showed that TGF-β1 strongly induced the phosphorylation of FAK, Src, and paxillin, while KY-05009 inhibited these inductions."
25337707
sparser
"However, the phosphorylation of Src was induced by TGF-β1, and this induction was also inhibited by the addition of CX-4945."
24023938
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"In this study, Src expression was not changed by TGF-β1 or TGF-β1 plus CX-4945, although CX-4945 did inhibit the TGF-β1-induced phosphorylation of Src."
24023938
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"However, the phosphorylation of Src was induced by TGF-beta1, and this induction was also inhibited by the addition of CX-4945."
24023938