IndraLab

Statements


IKBKB phosphorylates CYLD. 3 / 3
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reach
"Previous work demonstrated that TNF-alpha induces IKKalpha- and IKKbeta mediated serine phosphorylation of CYLD (Ser 418) [49]."

sparser
"Seminal work by Sun and colleagues showed that CYLD was phosphorylated by IKKβ and this inhibited its catalytic activity xref ."

reach
"Interestingly, IKKalpha (I kappa B kinase alpha) and IKKbeta (I kappa B kinase beta) are also able to phosphorylate CYLD invitro, although invivo they require additional assistance of IKKgamma."