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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

IFI30 activates KCNMA1. 2 / 2

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"Phagocytosis of hemolysin expressing organisms may not be essential for activation of the lytic activity, as we have recently found that Toll like receptor (TLR)-mediated activation of macrophages by E. coli lipopolysaccharide induces secretion of the enzymatically-active precursor form of GILT XREF_BIBR, XREF_BIBR that activates SLO in vitro (XREF_SUPPLEMENTARY)."

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"The ability of GILT to activate SLO as well as LLO suggests that it may activate other members of this highly conserved family of hemolysins."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...