IndraLab

Statements

IFI30 activates KCNMA1. 2 / 2
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"The ability of GILT to activate SLO as well as LLO suggests that it may activate other members of this highly conserved family of hemolysins."
18815593
reach
"Phagocytosis of hemolysin expressing organisms may not be essential for activation of the lytic activity, as we have recently found that Toll like receptor (TLR)-mediated activation of macrophages by E. coli lipopolysaccharide induces secretion of the enzymatically-active precursor form of GILT XREF_BIBR, XREF_BIBR that activates SLO in vitro (XREF_SUPPLEMENTARY)."
18815593