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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP24 activates ATP-binding cassette. 1 / 1

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eidos

"Herein , we found that USP24 not only repressed DNA-damage repair ( DDR ) activity by decreasing Rad51 expression to cause the tumor genomic instability and cancer stemness , but also increased the levels of the ATP-binding cassette ( ABC ) transporters P-gp , ABCG2 , and ezrin to enhance the pumping out of Taxol from cancer cells , thus resulted in drug resistance during cancer therapy ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...