IndraLab

Statements


USP16 decreases the amount of oxalate(1-). 2 / 2
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"Given that previous studies indicate that H2A ubiquitination regulates Hox gene silencing, it is possible that Usp16 may repress Hox gene expression by modulating the levels of uH2A at the promoter and 5 ' end regulatory region of the Hox gene Finally, there is recent evidence that, in addition to a role in silencing, uH2A may also control transcriptional initiation."

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"Knockdown of Usp16 causes a decrease in Hox expression and the rescue from this defect requires the deubiquitinating activity of Usp16."