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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

BRAF-V600E activates MAPK1. 1 / 4

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"About 50% of papillary thyroid carcinomas (PTC) harbor activating mutations in the BRAF gene (mostly BRAF V600E), an effector of MEK that in turn activates the ERK1 and ERK2 mitogen activated protein kinases."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...