IndraLab

No evidence text available

"XREF_BIBR USP53 interacts with DDB2, but knockdown of USP53 has no effect on DDB2 stability."

"Interestingly, we also confirmed that USP53 interacts with DDB2 by co-immunoprecipitation ( xref )."

"Thus, the physiological relevance of USP53-DDB2 interactions is unclear."

No evidence text available

"Interestingly, we also confirmed that USP53 interacts with DDB2 by co-immunoprecipitation (XREF_FIG)."

"USP53 interacts with DDB2, but knockdown of USP53 has no effect on DDB2 stability."

"Damage-specific DNA binding protein 2 (DDB2) is involved in nucleotide excision repair, which can repair DNA damage, and prevent gene mutation and tumorigenesis. xref Zou et al showed that knockdown of DDB2 expression in human lung cancer cells decreases the G2 phase and the repair efficiency of homologous recombination to increase the sensitivity of lung cancer cells to radiotherapy. xref Damage-specific DNA binding protein has been shown to interact with USP53, although the physiological relevance of USP53–DDB2 interactions remains unclear. xref In this study, we knocked down USP53 to provide evidence that the relationship between USP53 and DDB2 increases the radiosensitivity of cervical squamous cell carcinoma."