IndraLab

Statements


STK11 phosphorylates TP53 on S15. 7 / 8
1 1 | 4 1

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"Furthermore, LKB1, the upstream activator of AMPK, directly or indirectly phosphorylates p53 at Ser15 and Ser392, and activates the transcription of p21 following UV treatment (Zeng and Berger, 2006)."

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"The tumor suppressor LKB1, a serine/threonine kinase which associates with and phosphorylates p53 at Ser 15 and -392, promotes cell cycle arrest in G 1 through p21 [XREF_BIBR]."

sparser
"Furthermore, LKB1, the upstream activator of AMPK, directly or indirectly phosphorylates p53 at Ser15 and Ser392, and activates the transcription of p21 following UV treatment (Zeng and Berger, 2006)."

No evidence text available

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"Zeng et al reported that LKB1 physically associates with p53 in the nucleus and phosphorylates p53 at the amino acid residues Ser15 and Ser392."

"We show that lkb1 physically associates with p53 in the nucleus and directly or indirectly phosphorylates p53 ser15 (previously shown to be phosphorylated by amp-dependent kinase) and p53 ser392"

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"We show that LKB1 physically associates with p53 in the nucleus and directly or indirectly phosphorylates p53 Ser15 (previously shown to be phosphorylated by AMP dependent kinase) and p53 Ser392."