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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CTNNB1 binds GDNF, GFRA1, and RET. 1 / 1

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"However, molecular studies in human HEK293 and neuroblastoma cell lines demonstrated a GDNF/GFRα1-induced interaction between RET and β-catenin at the plasma membrane, resulting in tyrosine phosphorylation of β-catenin which prevents its proteasomal degradation, and results in cell survival and proliferation ( xref )."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...