IndraLab

Statements

USP10 binds G3BP2, G3BP1, and CAPRIN1. 6 / 6
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"In addition, a proteomic analysis found that G3BP1, G3BP2, Caprin1 and USP10 interact with DENV RNA [ xref ], and it was reported that G3BP1, G3BP2 and Caprin1 regulate the translation of ISG mRNAs, thus protecting DENV replication from IFN-mediated antiviral effects [ xref ]."
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"However, a role for the G3BP1 and G3BP2 interactions with CAPRIN1 and/or USP10 under chronic nutrient starvation has not yet been investigated."
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"ZIKV infection induces the redistribution of TIAR to the viral RNA replication sites (Hou et al.2017); SeV Trailer RNA captures TIAR from SG (Iseni et al.2002); West Nile Virus (WNV) and Dengue virus (DENV) 3′-end viral genome captures TIA-1/TIAR (Li et al.2002; Emara and Brinton 2007; Xia et al.2015); DENV 3′-UTR interacts with G3BP1, G3BP2, Caprin1 and USP10 (Ward et al.2011; Reineke et al.2015); JEV recruits G3BP and USP10 to the perinuclear region through the interaction of JEV core protein with Caprin-1, a SG-associated cellular factor (Ward et al.2011)."
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"ZIKV infection induces the redistribution of TIAR to the viral RNA replication sites (Hou et al. 2017) ; SeV Trailer RNA captures TIAR from SG (Iseni et al. 2002) ; West Nile Virus (WNV) and Dengue virus (DENV) 3 0 -end viral genome captures TIA-1/TIAR (Li et al. 2002; Emara and Brinton 2007; Xia et al. 2015) ; DENV 3 0 -UTR interacts with G3BP1, G3BP2, Caprin1 and USP10 (Ward et al. 2011; Reineke et al. 2015) ; JEV recruits G3BP and USP10 to the perinuclear region through the interaction of JEV core protein with Caprin-1, a SG-associated cellular factor (Ward et al. 2011) ."
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"Additional experiments demonstrate that, in contrast to DDX6, the SG proteins G3BP1, G3BP2, Caprin1 and USP10 bind to the variable region (VR) in the 3' UTR."
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"In addition, a proteomic analysis found that G3BP1, G3BP2, Caprin1 and USP10 interact with DENV RNA [171], and it was reported that G3BP1, G3BP2 and Caprin1 regulate the translation of ISG mRNAs, thus protecting DENV replication from IFN-mediated antiviral effects [172]."
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