IndraLab

Statements

WDR20 activates ZUP1. 2 / 2
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reach
"WDR48 and WDR20 bind the DUBs relatively far from the catalytic cleft and stimulate DUB catalytic activity via allosteric mechanisms (Figure 1; Yin et al., 2015; Dharadhar et al., 2016; Li et al., 2016)."
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eidos
"The DUB can be further activated by WDR20 , which anchors at the base of BL1 but allosterically regulates the conformation of BL2 and the catalytic cleft ."
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